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Open World Class Institute KBSI

자기공명 분야

Home > 주요연구사업 > 연구개발 > 연구분야 > 생명과학 > 자기공명 분야

자기공명 분야 Nuclear Magnetic Resonance Research

생체물질의 입체구조 분석, 상호작용 및 동력학 연구를 위해 NMR 장비를 활용하고, 구조기반 신약 발굴 원천기술 개발연구를 수행하였습니다.

자기공명연구단

주요수행연구

거대 생체분자 구조분석과 생체분자 상호작용 측정을 위해 NMR 기술들을 개발하였고, 이를 활용하여 국내외 연구팀과 공동연구를 수행하여 총 29편의 논문을 발표하였습니다.

대표적 연구사례

미생물의 Quorum Sensing 결합구조 분석 및 메커니즘 검증

미생물의 Quorum Sensing 관련 단백질(LsrR)과 Phospho-AI-2 등과의 결합구조를 밝혀 Sensing 메커니즘 검증하였습니다.

LsrR tetramer와 C-Lsr dimer의 겹침구조

관련장비

  • 900 MHz 핵자기공명분광기
  • 800 MHz 핵자기공명분광기
  • 700 MHz 핵자기공명분광기
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